RhBMP-7 improves survival and eruption in a growing tooth avulsion trauma model.

@article{Springer2005RhBMP7IS,
  title={RhBMP-7 improves survival and eruption in a growing tooth avulsion trauma model.},
  author={I. N. Springer and Yahya Açil and Christian Spies and Soeren Jepsen and P. H. Warnke and Hendrik Bolte and Solveig Kuchenbecker and Paul Anthony John Russo and J. Wiltfang and H. Terheyden},
  journal={Bone},
  year={2005},
  volume={37 4},
  pages={570-7}
}
Long-term loss of avulsed and replanted teeth is a frequent clinical problem. Bone morphogenetic protein-7 (BMP 7) induces cementogenesis in periodontitis-associated periodontal ligament (PDL) defects. This study's aim was to assess the utility of rhBMP 7 in a tooth avulsion trauma model in growing individuals. Immature primary incisors of 12 minipigs were extracted. PDL and cementum were removed either partially (group 1: 4 mm2 [n=28 teeth]; group 2: 16 mm2 [n=26 teeth]) or totally (group 3 [n… CONTINUE READING

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