RhBMP-2 microspheres-loaded chitosan/collagen scaffold enhanced osseointegration: an experiment in dog.

@article{Shi2009RhBMP2MC,
  title={RhBMP-2 microspheres-loaded chitosan/collagen scaffold enhanced osseointegration: an experiment in dog.},
  author={Shanshan Shi and Xiangrong Cheng and Jiawei Wang and Wei Zhang and Lin Peng and Yufeng Zhang},
  journal={Journal of biomaterials applications},
  year={2009},
  volume={23 4},
  pages={331-46}
}
The purpose of this study is to develop a novel recombinant human bone morphogenetic protein-2 (rhBMP-2) sustained release scaffold for dental implant osseointegration, and to evaluate the effect of this scaffold on promoting bone formation. RhBMP-2 was encapsulated in the poly-D,L-lactide-co-glycolide (PLGA) biodegradable microspheres, which were… CONTINUE READING