Rh[III]-catalyzed C-H amidation using aroyloxycarbamates to give N-Boc protected arylamines.

@article{Grohmann2013RhIIIcatalyzedCA,
  title={Rh[III]-catalyzed C-H amidation using aroyloxycarbamates to give N-Boc protected arylamines.},
  author={Christoph Grohmann and Honggen Wang and Frank Glorius},
  journal={Organic letters},
  year={2013},
  volume={15 12},
  pages={3014-7}
}
The Rh(III)-catalyzed amidation of C(sp(2))-H bonds by the use of electron-deficient aroyloxycarbamates as efficient electrophilic amidation partners is reported. The reaction proceeded under mild conditions with broad functional group tolerance, and pyridine and O-methyl hydroxamic acids serve as efficient directing groups, giving access to valuable N-Boc… CONTINUE READING