Reward unpredictability inside and outside of a task context as a determinant of the responses of tonically active neurons in the monkey striatum.

Tonically active neurons (TANs) in the monkey striatum are involved in detecting motivationally relevant stimuli. We recently provided evidence that the timing of conditioned stimuli strongly influences the responsiveness of TANs, the source of which is likely to be the monkey's previous experience with particular temporal regularities in sequential task… (More)