Reward Responsiveness Varies by Smoking Status in Women with a History of Major Depressive Disorder

@article{Janes2015RewardRV,
  title={Reward Responsiveness Varies by Smoking Status in Women with a History of Major Depressive Disorder},
  author={Amy C. Janes and Paola Pedrelli and Alexis E Whitton and Pia Pechtel and Samuel R Douglas and Max A Martinson and Ilana Huz and Maurizio Fava and Diego A. Pizzagalli and Anne Eden Evins},
  journal={Neuropsychopharmacology},
  year={2015},
  volume={40},
  pages={1940-1946}
}
Major depressive disorder (MDD) and nicotine dependence are highly comorbid, with studies showing that ~50% of individuals with MDD smoke. The link between these disorders persists even after the clinical symptoms of depression subside, as indicated by high levels of nicotine dependence among individuals with remitted depression (rMDD). Recent evidence indicates that individuals with rMDD show blunted responses to reward as measured by a probabilistic reward task (PRT), which assesses the… CONTINUE READING
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