Revisiting traditional risk factors for rejection and graft loss after kidney transplantation.

  title={Revisiting traditional risk factors for rejection and graft loss after kidney transplantation.},
  author={Ty B Dunn and Harriet J. Noreen and Kristen J. Gillingham and David Alan Maurer and Ozlem Goruroglu Ozturk and Timothy L. Pruett and Robert A. Bray and Howard M. Gebel and Arthur J. Matas},
  journal={American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons},
  volume={11 10},
Single-antigen bead (SAB) testing permits reassessment of immunologic risk for kidney transplantation. Traditionally, high panel reactive antibody (PRA), retransplant and deceased donor (DD) grafts have been associated with increased risk. We hypothesized that this risk was likely mediated by (unrecognized) donor-specific antibody (DSA). We grouped 587 kidney transplants using clinical history and single-antigen bead (SAB) testing of day of transplant serum as (1) unsensitized; PRA = 0 (n = 178… CONTINUE READING


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Clinical relevance of pretransplant donor-specific HLA antibodies detected by single-antigen flow-beads

  • P Amico, G Honger, M Mayr, J Steiger, H Hopfer, S. Schaub
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