Revisiting the yeast PPR proteins--application of an Iterative Hidden Markov Model algorithm reveals new members of the rapidly evolving family.

@article{Lipinski2011RevisitingTY,
  title={Revisiting the yeast PPR proteins--application of an Iterative Hidden Markov Model algorithm reveals new members of the rapidly evolving family.},
  author={Kamil Andrzej Lipinski and Olga Puchta and Vineeth Surendranath and Marek Kudla and Pawel Golik},
  journal={Molecular biology and evolution},
  year={2011},
  volume={28 10},
  pages={2935-48}
}
Pentatricopeptide repeat (PPR) proteins are the largest known RNA-binding protein family, and are found in all eukaryotes, being particularly abundant in higher plants. PPR proteins localize mostly to mitochondria and chloroplasts, and many were shown to modulate organellar genome expression on the posttranscriptional level. Although the genomes of land plants encode hundreds of PPR proteins, only a few have been identified in Fungi and Metazoa. As the current PPR motif profiles are built… CONTINUE READING

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