Revisiting the role of yeast Sfp1 in ribosome biogenesis and cell size control: a chemostat study.

@article{Cipollina2008RevisitingTR,
  title={Revisiting the role of yeast Sfp1 in ribosome biogenesis and cell size control: a chemostat study.},
  author={Chiara Cipollina and Joost van den Brink and Pascale A. S. Daran-Lapujade and Jack T. Pronk and Marina Vai and Johannes H. De Winde},
  journal={Microbiology},
  year={2008},
  volume={154 Pt 1},
  pages={337-46}
}
Saccharomyces cerevisiae SFP1 promotes transcription of a large cluster of genes involved in ribosome biogenesis. During growth in shake flasks, a mutant deleted for SFP1 shows a small size phenotype and a reduced growth rate. We characterized the behaviour of an sfp1Delta mutant compared to an isogenic reference strain growing in chemostat cultures at the same specific growth rate. By studying glucose (anaerobic)- and ethanol (aerobic)-limited cultures we focused specifically on nutrient… CONTINUE READING

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