Revisiting the glyoxylate cycle: alternate pathways for microbial acetate assimilation

@article{Ensign2006RevisitingTG,
  title={Revisiting the glyoxylate cycle: alternate pathways for microbial acetate assimilation},
  author={S. Ensign},
  journal={Molecular Microbiology},
  year={2006},
  volume={61}
}
  • S. Ensign
  • Published 2006
  • Biology, Medicine
  • Molecular Microbiology
  • The glyoxylate cycle, identified by Kornberg et al. in 1957, provides a simple and efficient strategy for converting acetyl‐CoA into anapleurotic and gluconeogenic compounds. Studies of a number of bacteria capable of growth with C2 compounds as the sole carbon source have revealed that they lack the key glyoxylate cycle enzyme isocitrate lyase, suggesting that alternative pathway(s) for acetate assimilation exist in these bacteria. Recent studies of acetate assimilation in methylotrophs and… CONTINUE READING
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    References

    SHOWING 1-10 OF 10 REFERENCES
    Study of an alternate glyoxylate cycle for acetate assimilation by Rhodobacter sphaeroides
    • 100
    • Highly Influential
    Glyoxylate regeneration pathway in the methylotroph Methylobacterium extorquens AM1.
    • 98
    • Highly Influential
    • PDF
    The formation of isocitratase by the Athiorhodaceae.
    • 57
    • PDF
    Acetate metabolism in Rhodopseudomonas gelatinosa and several other Rhodospirillaceae
    • 40
    The glyoxylate cycle as a stage in the conversion of fat to carbohydrate in castor beans.
    • 155
    Mixotrophic growth of Thiobacillus A2 on acetate and thiosulfate as growth limiting substrates in the chemostat
    • 42
    Synthesis of Cell Constituents from C2-Units by a Modified Tricarboxylic Acid Cycle
    • 460