• DOI:10.1345/aph.1A208
Corpus ID: 20855578

Revisiting the Significance of Warfarin Protein-Binding Displacement Interactions

@article{Sands2002RevisitingTS,
  title={Revisiting the Significance of Warfarin Protein-Binding Displacement Interactions},
  author={Charles D Sands and E. S. Chan and T. Welty},
  journal={Annals of Pharmacotherapy},
  year={2002},
  volume={36},
  pages={1642 - 1644}
}

Charles D Sands, E. S. Chan, T. Welty

Published 2002

Medicine

Annals of Pharmacotherapy

Most clinicians who manage patients on warfarin therapy are aware of the transient nature of changes in the prothrombin time (PT) secondary to protein-binding displacement interactions. However, anecdotal case reports and clinical impressions by some healthcare professionals continue to inflate, on occasion, the importance of warfarin protein-binding displacement interactions,1 despite the fact that the transient nature of the interaction has been well described for >30 years.2-7 Thus, it is… CONTINUE READING

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