Revisiting Criteria for Plant MicroRNA Annotation in the Era of Big Data.

@article{Axtell2018RevisitingCF,
  title={Revisiting Criteria for Plant MicroRNA Annotation in the Era of Big Data.},
  author={Michael J. Axtell and Blake C. Meyers},
  journal={The Plant cell},
  year={2018},
  volume={30 2},
  pages={272-284}
}
MicroRNAs (miRNAs) are ∼21-nucleotide-long regulatory RNAs that arise from endonucleolytic processing of hairpin precursors. Many function as essential posttranscriptional regulators of target mRNAs and long noncoding RNAs. Alongside miRNAs, plants also produce large numbers of short interfering RNAs (siRNAs), which are distinguished from miRNAs primarily by their biogenesis (typically processed from long double-stranded RNA instead of single-stranded hairpins) and functions (typically via… CONTINUE READING