Revisiting Castlio and Ferris-Swift's experiments testing the effects of splenic pump in normal individuals

@article{Noll2005RevisitingCA,
  title={Revisiting Castlio and Ferris-Swift's experiments testing the effects of splenic pump in normal individuals},
  author={Donald R. Noll and Jane C. Johnson},
  journal={International Journal of Osteopathic Medicine},
  year={2005},
  volume={8},
  pages={124-130}
}
Abstract Background Castlio and Ferris-Swift conducted a series of experiments in the 1930s testing the scientific basis for using splenic pump manipulation to stimulate the immune system. Their work is still cited as evidence that the splenic pump technique is beneficial. However, they only reported case summaries of the data, indicating what percent of the cases increased or decreased relative to baseline and, therefore, limiting the certainty of their conclusions. To our knowledge, no one… Expand
Revisiting Castlio and Ferris-Swift's Experiments on Direct Splenic Stimulation in Patients With Acute Infectious Disease
TLDR
Analysis of Castlio and Ferris-Swift's 1934 data using contemporary statistical methods supports many of their original conclusions, however, faults in study design common to that era limit the article's applicability for modern researchers. Expand
Short-Term Hematologic and Hemodynamic Effects of Osteopathic Lymphatic Techniques
  • Donald R. Noll
  • Medicine
  • The Journal of the American Osteopathic Association
  • 2009
TLDR
Comprehensive lymphatic treatments were reported to decrease mortality rates during the influenza pandemic of 1918, and this statement is referenced with a 1920 JAOA article by R. Kendrick Smith, MD, DO, however, this reference citation is misleading. Expand
Osteopathic Manipulative Therapy Induces Early Plasma Cytokine Release and Mobilization of a Population of Blood Dendritic Cells
TLDR
The results show that OMT was not able to induce a rapid modification in the levels of plasma nitrites or CRP or in the proportion or activation status of central memory, effector memory or naïve CD4 and CD8 T cells. Expand
The Short-Term Effect of a Lymphatic Pump Protocol on Blood Cell Counts in Nursing Home Residents With Limited Mobility: A Pilot Study
  • Donald R. Noll
  • Medicine
  • The Journal of the American Osteopathic Association
  • 2013
TLDR
The OMT protocol used in this pilot study modestly reduced platelet counts in nursing home residents with limited mobility and was not statistically significant relative to the control group. Expand
Rediscovering the classic osteopathic literature to advance contemporary patient-oriented research: A new look at diabetes mellitus
TLDR
The re-analysis of Bandeen's 1949 raw data described herein summarizes the effects of osteopathic manipulative treatment involving pancreatic stimulatory and inhibitory techniques in diabetic and non-diabetic patients seen over a 25-year period of clinical practice. Expand
Osteopathic manipulative therapy and its role to enhance the immune response of the body, modification the plasma level of cytokines, Cortisol and Serotonin ; and its positive effect on the anti – infection, anti -stress and anti- inflammatory responses
  • 2014
Osteopathic medicine is based on the premise that the primary role of it is to facilitate the body’s inherent ability to heal itself. These manipulative therapies have been successfully used byExpand

References

SHOWING 1-7 OF 7 REFERENCES
Effect of lymphatic and splenic pump techniques on the antibody response to hepatitis B vaccine: a pilot study.
TLDR
Data suggest an enhanced immunologic response in subjects who received OMT, and the average anti-hepatitis B titer was higher in the treatment group than in the control group. Expand
Transient basophilia following the application of lymphatic pump techniques: a pilot study.
TLDR
Lymphatic pump techniques consisting of pectoral traction and splenic pump were performed on seven male medical students following blood collection for baseline value determinations and all subjects showed an increase in the percentage of basophils. Expand
Thoracic lymphatic pumping and the efficacy of influenza vaccination in healthy young and elderly populations
TLDR
The authors' findings suggest that TLP in conjunction with influenza vaccination does not enhance immunization against influenza in otherwise healthy and active populations, however, such techniques may be of value when applied in conjunctionWith vaccination to nonambulatory patients or on actual influenza exposure of at-risk individuals. Expand
The effects of manually applied intermittent pulsation pressure to rat ventral thorax on lymph transport.
TLDR
It is demonstrated that mechanical pressure to body regions physically distant from the location of lymph formation enhances lymph uptake. Expand
Benefits of osteopathic manipulative treatment for hospitalized elderly patients with pneumonia
TLDR
The treatment group had a significantly shorter duration of intravenous antibiotic treatment and a shorter hospital stay than the control group, and there was no statistical difference between groups for age, sex, or simplified acute physiology scores. Expand