Revisit dietary fiber on colorectal cancer: butyrate and its role on prevention and treatment

  title={Revisit dietary fiber on colorectal cancer: butyrate and its role on prevention and treatment},
  author={Jo{\~a}o Crispim Encarnaç{\~a}o and Ana Margarida Coelho Abrantes and Ana Salom{\'e} Pires and Maria Filomena Botelho},
  journal={Cancer and Metastasis Reviews},
Colorectal cancer is still a major health problem worldwide. Based on the most recent released data by the World Health Organization GLOBOCAN in 2012, colorectal cancer is the third most prevalent type of cancer in males and the second in females. In 1999, it was published the first report showing evidence of a strong correlation between diet and cancer incidence, being its positive or negative impact intimately linked to dietary patterns. A diet rich in fiber is associated with a low risk of… 

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