Revised translation start site for secM defines an atypical signal peptide that regulates Escherichia coli secA expression.

@article{Sarker2000RevisedTS,
  title={Revised translation start site for secM defines an atypical signal peptide that regulates Escherichia coli secA expression.},
  author={Shameema S. Sarker and Kenneth E. Rudd and Donald Oliver},
  journal={Journal of bacteriology},
  year={2000},
  volume={182 19},
  pages={5592-5}
}
The secretion-responsive regulation of Escherichia coli secA occurs by coupling its translation to the translation and secretion of an upstream regulator, secM (formerly geneX). We revise the translational start site for secM, defining a new signal peptide sequence with an extended amino-terminal region. Mutational studies indicate that certain atypical… CONTINUE READING