Revised guides for organ sampling and trimming in rats and mice--part 1.

@article{RuehlFehlert2003RevisedGF,
  title={Revised guides for organ sampling and trimming in rats and mice--part 1.},
  author={Christine I Ruehl-Fehlert and Birgit Kittel and Gerd Morawietz and Paul Deslex and Charlotte Keenan and Charles R Mahrt and Thomas Nolte and Mervyn Robinson and Barry P Stuart and Ulrich Deschl},
  journal={Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie},
  year={2003},
  volume={55 2-3},
  pages={91-106}
}
This is the first part of a series of three articles on trimming instructions of rat and mouse protocol organs and tissues in regulatory type toxicity studies. It is based on the experience made in the European RITA and American NACAD working groups and is an extended revision of trimming guides published in 1995 (Bahnemann et al.). The optimum localization for tissue preparation, the sample size, the direction of sectioning and the number of sections to be prepared is described organ by organ… CONTINUE READING