Revised genomic structure of the human ghrelin gene and identification of novel exons, alternative splice variants and natural antisense transcripts

@article{Seim2007RevisedGS,
  title={Revised genomic structure of the human ghrelin gene and identification of novel exons, alternative splice variants and natural antisense transcripts},
  author={Inge Seim and Chris Collet and Adrian C. Herington and Lisa Chopin},
  journal={BMC Genomics},
  year={2007},
  volume={8},
  pages={298 - 298}
}
Ghrelin is a multifunctional peptide hormone expressed in a range of normal tissues and pathologies. It has been reported that the human ghrelin gene consists of five exons which span 5 kb of genomic DNA on chromosome 3 and includes a 20 bp non-coding first exon (20 bp exon 0). The availability of bioinformatic tools enabling comparative analysis and the finalisation of the human genome prompted us to re-examine the genomic structure of the ghrelin locus. We have demonstrated the presence of an… CONTINUE READING

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