Reviewer's report Title: Physiological Effects of Ghrelin in Cachectic COPD: substudy of a multicenter, randomized, double-blind, placebo-controlled trial of ghrelin treatment


In the present study the authors describe that a 3-week treatment with Ghrelin bd significantly increased maximal oxygen-uptake in COPD-patients with improved exertional capacity and improvements in ventilatory-cardiac parameters. The present results were retrieved from 10 patients (single center) and 10 controls out of a multicenter study that comprised 33… (More)


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