Review of tumoral calcinosis: A rare clinico-pathological entity.

  title={Review of tumoral calcinosis: A rare clinico-pathological entity.},
  author={Ibrahim Fathi and Mahmoud Fathy Sakr},
  journal={World journal of clinical cases},
  volume={2 9},
Tumoral calcinosis (TC) has long been a controversial clinico-pathological entity. Its pathogenesis and genetic background have been gradually unravelled since its first description in 1943. According to the presence or absence of an underlying calcifying disease process, TC has been divided into primary and secondary varieties. Two subtypes of the primary variety exist; a hyper-phosphatemic type with familial basis represented by mutations in GalNAc transferase 3 gene (GALNT3), KLOTHO or… CONTINUE READING


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