Review of the secondary injury theory of acute spinal cord trauma with emphasis on vascular mechanisms.

@article{Tator1991ReviewOT,
  title={Review of the secondary injury theory of acute spinal cord trauma with emphasis on vascular mechanisms.},
  author={Charles Tator and Michael G. Fehlings},
  journal={Journal of neurosurgery},
  year={1991},
  volume={75 1},
  pages={
          15-26
        }
}
In patients with spinal cord injury, the primary or mechanical trauma seldom causes total transection, even though the functional loss may be complete. In addition, biochemical and pathological changes in the cord may worsen after injury. To explain these phenomena, the concept of the secondary injury has evolved for which numerous pathophysiological mechanisms have been postulated. This paper reviews the concept of secondary injury with special emphasis on vascular mechanisms. Evidence is… 

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