Review of the safety, efficacy, and pharmacokinetics of elvitegravir with an emphasis on resource-limited settings

  title={Review of the safety, efficacy, and pharmacokinetics of elvitegravir with an emphasis on resource-limited settings},
  author={Janice Soo Fern Lee and Alexandra Calmy and Isabelle Andrieux-Meyer and Nathan Ford},
Integrase inhibitors represent an important new class of antiretroviral drugs. Elvitegravir, the second available integrase inhibitor to be submitted for regulatory approval appears to be a promising once-daily agent when combined with other antiretroviral drugs. Elvitegravir has demonstrated good efficacy and safety, with minimal side effects and no specific requirements in terms of laboratory monitoring. In addition, elvitegravir is available as a fixed-dose combination. However, the drug… CONTINUE READING
5 Citations
47 References
Similar Papers


Publications referenced by this paper.
Showing 1-10 of 47 references

A pharmacokinetic interaction between lopinavir/r and elvitegravir

  • A Mathias, S West, J Enejosa, B. Kearney
  • 47th Interscience Conference on Antimicrobial…
  • 2007
Highly Influential
3 Excerpts

Gilead’s Investigational Antiretroviral Quad Regimen Meets 48-Week Primary Objective in Pivotal Phase 3 Clinical Study 102

  • Gilead Sciences
  • Press release. August
  • 2011
1 Excerpt

HIV , Hepatitis C Virus ( HCV ) , and tuberculosis drugs , diagnostics , vaccines , and preventive technologies in development

  • P Clayden, S Collins, M Harrington
  • Guidelines for the Use of Antiretroviral Agents…
  • 2011

HIV, Hepatitis C Virus (HCV), and tuberculosis drugs, diagnostics, vaccines, and preventive technologies in development. 2011 pipeline report second edition

  • P Clayden, S Collins, M Harrington
  • 2011
1 Excerpt

Pharmacokinetic interaction between norgestimate/ethinyl estradiol and EVG/COB/FTC/TDF single tablet regimen

  • P German, M Wang, D Warren, PB. Kearney
  • 12th International Workshop on Clinical…
  • 2011
1 Excerpt

Similar Papers

Loading similar papers…