Review of the apoptosis pathways in pancreatic cancer and the anti-apoptotic effects of the novel sea cucumber compound, Frondoside A.

@article{Li2008ReviewOT,
  title={Review of the apoptosis pathways in pancreatic cancer and the anti-apoptotic effects of the novel sea cucumber compound, Frondoside A.},
  author={Xinquan Li and Alexandra B Roginsky and X-Z Ding and Carl Woodward and Peter Collin and Robert A. Newman and Richard H. Bell and Thomas Edward Adrian},
  journal={Annals of the New York Academy of Sciences},
  year={2008},
  volume={1138},
  pages={181-98}
}
Pancreatic cancer cells are resistant to the growth-inhibitory and apoptosis-inducing effects of conventional chemotherapeutic agents. There are multiple genetic and epigenetic events during the process of carcinogenesis that enable the cancer cells to avoid normal growth constraints and apoptosis. Investigation of the mechanisms involved has led to multiple strategies that encourage cell death and apoptosis to occur. The pathways involved are summarized in this review, together with some… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 1 time. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 29 extracted citations

Pharmacological Potential of Sea Cucumbers

International journal of molecular sciences • 2018
View 5 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…