Review of studies evaluating ductal patency in the premature infant.

@article{Reller1993ReviewOS,
  title={Review of studies evaluating ductal patency in the premature infant.},
  author={Mark D. Reller and Mary J. Rice and R W Mcdonald},
  journal={The Journal of pediatrics},
  year={1993},
  volume={122 6},
  pages={
          S59-62
        }
}
A series of investigations has been performed to assess the timing of physiologic closure of the ductus arteriosus in premature infants with and without respiratory distress syndrome. The data from these studies emphasize the concept of physiologic ductal patency and give normative data for expected closure rates through the fourth day of life. On the basis of these data, patency on or beyond the fourth day of life is abnormal irrespective of gestational age, and prematurity, in the absence of… CONTINUE READING

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