Review of patents on microneedle applicators.

  title={Review of patents on microneedle applicators.},
  author={Thakur Raghu Raj Singh and Nicholas J. Dunne and Eoin Cunningham and Ryan F Donnelly},
  journal={Recent patents on drug delivery & formulation},
  volume={5 1},
Transdermal drug delivery offers certain advantages over conventional oral or parenteral administration. However, transdermal delivery is not available to many promising therapeutic agents, especially high molecular weight hydrophilic compounds. This is due to the excellent barrier property of the superficial skin layer, the stratum corneum (SC). Only drugs with very specific physicochemical properties (molecular weight < 500 Da, adequate lipophilicity, and low melting point) can be… CONTINUE READING
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