Review of fungus-induced asthmatic reactions.

  title={Review of fungus-induced asthmatic reactions.},
  author={Henk F. Kauffman and J F C Tomee and T S van der Werf and Jan G R de Monchy and Gerard Ko{\"e}ter},
  journal={American journal of respiratory and critical care medicine},
  volume={151 6},
  pages={2109-15; discussion 2116}
Fungus-induced obstructive airway disease in atopic individuals can be differentiated into two categories: first, uncomplicated asthmatic reactions due to high but transient exposure to fungal spores (fungal asthma), resulting in a TH2-type response with immunoglobulin E-mediated reactions and eosinophilic inflammation; and second, a more complex asthmatic reaction due to colonization of the mucus-epithelial surface by virulent protease-producing fungi. The latter condition stimulates as… CONTINUE READING


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