Review of first 5 years of screening for familial hypercholesterolaemia in the Netherlands

@article{UmansEckenhausen2001ReviewOF,
  title={Review of first 5 years of screening for familial hypercholesterolaemia in the Netherlands},
  author={M. A. Umans-Eckenhausen and J. Defesche and E. Sijbrands and R. L. Scheerder and J. Kastelein},
  journal={The Lancet},
  year={2001},
  volume={357},
  pages={165-168}
}
BACKGROUND Familial hypercholesterolaemia is a common lipid disorder that predisposes for premature cardiovascular disease (CVD). We set up a screening programme in the Netherlands in 1994 to: establish the feasibility of active family screening supported by DNA diagnostics; assess whether or not active identification of these patients with familial hypercholesterolaemia would lead to more cholesterol-lowering treatment; and compare diagnosis by DNA analysis with that by cholesterol measurement… Expand
384 Citations

Paper Mentions

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To test the hypothesis that in patients with a clinical diagnosis of familial hypercholesterolemia (FH), genetic testing and identification of a causative mutation might enhance… Expand
ConditionsHypercholesterolemia, Familial
InterventionOther
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