Review of experimental animal models of acute pancreatitis.

  title={Review of experimental animal models of acute pancreatitis.},
  author={Kim Hue Su and Christine M. Cuthbertson and Christopher Christophi},
  journal={HPB : the official journal of the International Hepato Pancreato Biliary Association},
  volume={8 4},
The underlying mechanisms involved in the pathogenesis of acute pancreatitis are ill understood. The mortality rate of this disease has not significantly improved over the past few decades. Current treatment options are limited, and predominantly aimed at supportive therapy. A key feature of severe acute pancreatitis is the presence of extensive tissue necrosis with both local and systemic manifestations of inflammatory response syndromes. A better understanding of the underlying… CONTINUE READING


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