Review of electronic cigarettes as tobacco cigarette substitutes: Their potential human health impact

@article{Kim2016ReviewOE,
  title={Review of electronic cigarettes as tobacco cigarette substitutes: Their potential human health impact},
  author={Ki‐Hyun Kim and Ehsanul Kabir and Shamin Ara Jahan},
  journal={Journal of Environmental Science and Health, Part C},
  year={2016},
  volume={34},
  pages={262 - 275}
}
ABSTRACT Electronic cigarettes (ECs) are devised to deliver nicotine in a vapor rather than in smoke without tar. ECs are hence advertised as being safer than tobacco cigarette products as the chemical compounds inhaled in the former are believed to be fewer and less toxic than those of the latter. Hazardous chemicals (e.g., formaldehyde) are nonetheless found to be generated incidentally by contacting the heated wire (i.e., the oxidation of glycerol/glycol in e-liquid). Although the extent of… 
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14 Citations

Oral Carcinoma Associated with Chronic Use of Electronic Cigarettes

TLDR
Two cases of oral carcinoma associated with chronic use of E-cigarettes are reported and highlight the need for increased awareness of this important, and potentially fatal, risk.

E-cigarettes and cigarettes worsen peripheral and central hemodynamics as well as arterial stiffness: A randomized, double-blinded pilot study

TLDR
In this first of its kind trial, changes in peripheral and central blood pressure and also in pulse wave velocity after smoking a cigarette as well as after vaping a nicotine-containing electronic cigarette are observed and may be associated with an increased long-term cardiovascular risk.

Puff-resolved analysis and selected quantification of chemicals in the gas phase of E-Cigarettes, Heat-not-Burn devices and conventional cigarettes using single photon ionization time-of-flight mass spectrometry (SPI-TOFMS): A comparative study.

  • Jan HeideT. Adam Roger Zimmermann
  • Environmental Science
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
  • 2021
TLDR
The data shows that consumers switching from CC to ANDD are exposed to lower concentrations of harmful and potentially harmful substances, however, toxicological and epidemiological studies must deliver conclusive results if these reduced exposures are beneficial for users.

Heavy metals (Cr, Pb, Cd, Ni) in aerosols emitted from electronic cigarettes sold in Malaysia

TLDR
Five out of 100 combinations of ECIG and ECIG liquids were found to emit Cr that exceed the recommended PDE, and future studies examining more heavy metal variants, using a larger sample size and different analytical techniques to compare various ECIGs are recommended.

Oral mucosal lesions in electronic cigarettes consumers versus former smokers

TLDR
An increased prevalence of three specific types of OMLs was detected among ECs consumers.

Evaluation of e-liquid toxicity using an open-source high-throughput screening assay

TLDR
The data suggest that an HTS approach to evaluate the toxicity of multiple e-liquids is feasible and may serve as a roadmap to enable bodies such as the Food and Drug Administration (FDA) to better regulate e-liquid composition.

Analysis of the elements and metals in multiple generations of electronic cigarette atomizers.

Ocular conditions and dry eye due to traditional and new forms of smoking: A review.

Mitochondrial Stress Response in Neural Stem Cells Exposed to Electronic Cigarettes

In vitro RNA-seq-based toxicogenomics assessment shows reduced biological effect of tobacco heating products when compared to cigarette smoke

TLDR
THPs have a reduced impact on gene expression compared to 3R4F, and the relationship between the identified RNA features and gene ontologies were mapped showing a strong association with stress response, xenobiotics metabolism, and COPD-related terms for 3R 4F.

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TLDR
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