Review of drug interactions with telaprevir and antiretrovirals.

  title={Review of drug interactions with telaprevir and antiretrovirals.},
  author={R. P. G. van Heeswijk and Maria Beumont and Robert S. Kauffman and Varun Garg},
  journal={Antiviral therapy},
  volume={18 4},
HCV infection is a major cause of mortality worldwide. HCV-related deaths also represent a leading cause of mortality in HIV-coinfected individuals. Telaprevir is an NS3/4A protease inhibitor approved for the treatment of chronic HCV genotype 1 infection in adults in combination with pegylated interferon and ribavirin. Telaprevir-based treatment has been shown to increase rates of sustained viral response in HCV genotype-1-monoinfected patients, and studies in HCV-HIV-coinfected patients are… CONTINUE READING


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