Review of disrupted sleep patterns in Smith-Magenis syndrome and normal melatonin secretion in a patient with an atypical interstitial 17p11.2 deletion.

@article{Boudreau2009ReviewOD,
  title={Review of disrupted sleep patterns in Smith-Magenis syndrome and normal melatonin secretion in a patient with an atypical interstitial 17p11.2 deletion.},
  author={Eilis Ann Boudreau and Kyle P Johnson and Angela R. Jackman and Jan K Blancato and Marjan Huizing and Claude Bendavid and Marypat Jones and Settara C Chandrasekharappa and Alfred J. Lewy and Ann C. M. Smith and R. Ellen Magenis},
  journal={American journal of medical genetics. Part A},
  year={2009},
  volume={149A 7},
  pages={1382-91}
}
Smith-Magenis syndrome (SMS) is a disorder characterized by multiple congenital anomalies and behavior problems, including abnormal sleep patterns. It is most commonly due to a 3.5 Mb interstitial deletion of chromosome 17 band p11.2. Secretion of melatonin, a hormone produced by the pineal gland, is the body's signal for nighttime darkness. Published reports of 24-hr melatonin secretion patterns in two independent SMS cohorts (US and France) document an inverted endogenous melatonin pattern in… CONTINUE READING
13 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

Similar Papers

Loading similar papers…