Review of centrifugal liquid-liquid chromatography using aqueous two-phase solvent systems: its scale-up and prospects for the future production of high-value biologicals.

  • Ian Sutherland
  • Published 2007 in Current opinion in drug discovery & development

Abstract

Future challenges in the field of bioprocessing include developing new downstream processes for the purification and manufacture of protein-based medicines to relieve the predicted bottleneck that may occur as a result of increasingly high titers obtained from fermentation processes. This review considers recent developments in centrifugal liquid-liquid… (More)

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@article{Sutherland2007ReviewOC, title={Review of centrifugal liquid-liquid chromatography using aqueous two-phase solvent systems: its scale-up and prospects for the future production of high-value biologicals.}, author={Ian Sutherland}, journal={Current opinion in drug discovery & development}, year={2007}, volume={10 5}, pages={540-9} }