Review of Vertebral Augmentation: An Updated Meta-analysis of the Effectiveness

@article{Beall2018ReviewOV,
  title={Review of Vertebral Augmentation: An Updated Meta-analysis of the Effectiveness},
  author={D. Beall and M. Lorio and B. Yun and M. Runa and K. Ong and Christopher Warner},
  journal={International Journal of Spine Surgery},
  year={2018},
  volume={12},
  pages={295 - 321}
}
ABSTRACT Background: To update vertebral augmentation literature by comparing outcomes between vertebroplasty (VP), balloon kyphoplasty (BKP), vertebral augmentation with implant (VAI), and nonsurgical management (NSM) for treating vertebral compression fractures (VCFs). Methods: A PubMed literature search was conducted with keywords kyphoplasty, vertebroplasty, vertebral body stent, and vertebral augmentation AND implant for English-language articles from February 1, 2011, to November 22, 2016… Expand
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  • Medicine
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TLDR
Although both V and K have been shown to result in significantly better pain relief, higher quality of life scores, increased postoperative vertebral body height compared with NST, outcomes for all 3 groups remained the same. Expand
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TLDR
The authors' analyses from a state-level database of patients undergoing vertebroplasty and kyphoplasty for osteoporotic VCSs demonstrate similar postoperative-outcomes for the two procedures but a higher cost for kyPHoplasty. Expand
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TLDR
Given the abundance of high-quality information, ISASS can confidently advocate that there is strong support for vertebral augmentation in the treatment of symptomatic vertebral compression fractures. Expand
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TLDR
Analysis of the evidence shows, based on level I and II studies, balloon kyphoplasty had significantly better and vertebroplasty tended to have better pain reduction compared with non-surgical management. Expand
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The ISASS Policy Statement on vertebral augmentation has the objectives to provide a background and an update with the latest clinical evidence for the international spine community. A SpineLineExpand
Response to: The evidentiary basis of vertebral augmentation: a 2019 update
  • D. Beall
  • Medicine
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  • 2020
TLDR
The manuscript is an attempt to more objectively report some of the highly controversial and suboptimally constructed sham versus vertebroplasty articles. Expand
The "Optimum Volume" of Acrylic Cement Filling for Treating Vertebral Compression Fractures: A Morphometric Study of Thoracolumbar Vertebrae.
TLDR
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TLDR
It is suggested that racial and socioeconomic disparities continue to exist with the utilization of spine augmentation procedures in hospitalized patients with osteoporotic fractures. Expand
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TLDR
A significant decline in vertebral augmentation procedures in the fee-for-service Medicare population between 2004 and 2017 is illustrated, with dramatic decreases following the publication of two 2009 trials that failed to demonstrate benefit of vertebroplasty over sham and the enactment of the ACA. Expand
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Meta‐analysis of vertebral augmentation compared with conservative treatment for osteoporotic spinal fractures
TLDR
This meta‐analysis showed greater pain relief, functional recovery, and health‐related quality of life with cement augmentation compared with controls, and provided strong evidence in favor of cement augmented in the treatment of symptomatic VCF fractures. Expand
Comparing effects of kyphoplasty, vertebroplasty, and non-surgical management in a systematic review of randomized and non-randomized controlled studies
TLDR
BKP/VP provided greater pain relief and fewer subsequent fractures than NSM in osteoporotic VCFs and is marginally favored over VP in disability improvement, and significantly favored in QOL improvement. Expand
Comparing Percutaneous Vertebroplasty and Conservative Therapy for Treating Osteoporotic Compression Fractures in the Thoracic and Lumbar Spine: A Systematic Review and Meta-Analysis.
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The effect of PVP exceeded the effect of conservative therapy with respect to pain relief in patients with osteoporotic compression fractures up to 1 year postoperatively. Expand
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Compared with placebo, high- to moderate-quality evidence from five trials indicates that vertebroplasty provides no clinically important benefits with respect to pain, disability, disease-specific or overall quality of life or treatment success at one month. Expand
A Randomized Trial of Balloon Kyphoplasty and Nonsurgical Management for Treating Acute Vertebral Compression Fractures
TLDR
Compared with NSM, BKP improves patient quality of life and pain averaged during 24 months and results in better improvement of index vertebral body kyphotic angulation. Expand
Balloon Kyphoplasty Versus KIVA Vertebral Augmentation—Comparison of 2 Techniques for Osteoporotic Vertebral Body Fractures: A Prospective Randomized Study
TLDR
Both KIVA and BK restored in short-term similarly vertebral body height, but only KIVHr restored vertebra body wedge deformity, and long-term observation is needed to show whether these radiological changes have any functional impact. Expand
Comparison of Kyphoplasty and Vertebroplasty for Treatment of Painful Osteoporotic Vertebral Compression Fractures: Twelve-month Follow-up in a Prospective Nonrandomized Comparative Study
TLDR
Kyphoplasty offers a higher degree of spinal deformity correction and results in less cement leakage than vertebroplasty, and the benefits of these relative merits need to be ascertained in future long-term studies. Expand
Morbidity and Mortality After Vertebral Fractures: Comparison of Vertebral Augmentation and Nonoperative Management in the Medicare Population
TLDR
VCF patients in the Medicare population who received vertebral augmentation therapies, specifically BKP and VP, experienced lower mortality and overall morbidity than VCF patients who received conservative management. Expand
A comparison of two new technologies for percutaneous vertebral augmentation: confidence vertebroplasty vs. sky kyphoplasty.
TLDR
The SK system is technically superior in restoring the vertebral height and repairing the kyphotic deformity, an advantage that was not manifested in pain relief - the most important variable. Expand
A Randomized Trial Comparing Balloon Kyphoplasty and Vertebroplasty for Vertebral Compression Fractures due to Osteoporosis
TLDR
Kyphoplasty and vertebroplasty had similar long-term improvement in pain and disability with comparable safety profiles and few device-related complications and a trend toward longer fracture-free survival. Expand
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