Review of Pharmacological Effects of Antrodia camphorata and Its Bioactive Compounds

@article{Geethangili2011ReviewOP,
  title={Review of Pharmacological Effects of Antrodia camphorata and Its Bioactive Compounds},
  author={Madamanchi Geethangili and Yew-Min Tzeng},
  journal={Evidence-based Complementary and Alternative Medicine : eCAM},
  year={2011},
  volume={2011}
}
Antrodia camphorata is a unique mushroom of Taiwan, which has been used as a traditional medicine for protection of diverse health-related conditions. [...] Key Result The list of bioactivities of crude extracts is huge, ranging from anti-cancer to vasorelaxation and others. Over 78 compounds consisting of terpenoids, benzenoids, lignans, benzoquinone derivatives, succinic and maleic derivatives, in addition to polysaccharides have been identified. Many of these compounds were evaluated for biological activity…Expand
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References

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Antitumor effects of the partially purified polysaccharides from Antrodia camphorata and the mechanism of its action.
TLDR
It is suggested that AC-PS elicit its anti-tumor effect by promoting a Th1-dominant state and killer activities. Expand
Antioxidative and hepatoprotective effects of Antrodia camphorata extract.
TLDR
Results suggest that A. camphorata extract exerts effective protection against chronic chemical-induced hepatic injury in vivo, by mediating antioxidative and free radical scavenging activities. Expand
Immunomodulatory effect of Antrodia camphorata mycelia and culture filtrate.
TLDR
Results provide evidences that Antrodia camphorata can modulate innate immunity and may serve as an adjuvant for tumor treatment, and suggest that immunomodulatory effect of mycelia is mainly attributed to the 10-20kDa polysaccharides and adenosine. Expand
Niuchangchih (Antrodia camphorata) and its potential in treating liver diseases.
TLDR
The protective effects of Niuchangchih on the pathological development of liver diseases, and the underlying mechanisms of action are also discussed. Expand
Inhibitory effects of antrodins A–E from Antrodia cinnamomea and their metabolites on hepatitis C virus protease
TLDR
The results strongly support the use of this folk medicine for liver cancer and HCV infection which is a global problem. Expand
Antioxidant properties of Antrodia camphorata in submerged culture.
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TLDR
It was found that DMCM had lower antioxidant ability than DMF in different model systems, indicating that the major antioxidant components in DMF must be derived from the secondary metabolites of mycelia. Expand
Ganoderma - a therapeutic fungal biofactory.
TLDR
The biological activities reported of preparations from Ganoderma are remarkable and given most emphasis herein as distinct from structure/activity information. Expand
Antioxidant activity of Antrodia camphorata on free radical-induced endothelial cell damage.
TLDR
The findings suggest that A. camphorata possesses antioxidant properties and improves endothelial function, further offering effective protection from atherosclerosis. Expand
Evaluation of the anti-inflammatory activity of zhankuic acids isolated from the fruiting bodies of Antrodia camphorata.
TLDR
In conclusion, inhibition of both ROS production and firm adhesion by neutrophils has no significant cytotoxic effect that could give these drugs the potential to be anti-inflammatory agents for the clinical treatment. Expand
Anti-inflammatory activity of the extracts from mycelia of Antrodia camphorata cultured with water-soluble fractions from five different Cinnamomum species.
TLDR
It is suggested that extracts from cultured mycelia of A. camphorata display anti-inflammatory effects by inhibiting ROS production in human leukocytes at a pharmacologically applicable concentration. Expand
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