Review of Over-the-Counter Topical Scar Treatment Products

@article{Shih2007ReviewOO,
  title={Review of Over-the-Counter Topical Scar Treatment Products},
  author={Richard Shih and Joshua T. Waltzman and Gregory Evans},
  journal={Plastic and Reconstructive Surgery},
  year={2007},
  volume={119},
  pages={1091-1095}
}
Postsurgical, traumatic, and burn scars can be painful, pruritic, erythematous, raised, and cosmetically unacceptable. Although a number of over-the-counter products are available to treat symptomatic scars, the peer-reviewed data on the clinical efficacy of these products are limited and/or controv 
Pentoxifylline for the Prevention of Postsurgical Keloid Recurrence.
TLDR
Keloids are abnormal overgrowths of dermal fibrous tissue due to an exaggerated wound healing response after cutaneous insults that occur in patients with a high disease burden.
Comparison of the effectiveness of topical silicone gel and corticosteroid cream on the pfannenstiel scar prevention - a randomized controlled trial.
TLDR
The use of topical methylprednisolone cream in fresh wounds at the postoperative early period appears to be promising.
Evidence-Based Scar Management: How to Improve Results with Technique and Technology
TLDR
Although scars can never be completely eliminated in an adult, this article presents the most commonly used, evidence-based methods to improve the quality and symptoms of hypertrophic scars, as well as keloid scars and striae distensae.
The effect of topical scar treatment on postoperative scar pain and pruritus after total knee arthroplasty
TLDR
Application of silicone gel had no beneficial effects on scar pain and itching relief during the early postoperative period of TKA.
Reduction of postoperative scar formation with silicone sheeting: 2 case studies.
Update on hypertrophic scar treatment
TLDR
This review will explore the differences between different types of nonsurgical management of hypertrophic scars, focusing on the indications, uses, mechanisms of action, associations and efficacies of the following therapies: silicone, pressure garments, onion extract, intralesional corticoid injections and bleomycin.
Summary and evidence grading of over-the-counter scar treatments.
TLDR
Online advertising may tempt patients to buy and trial products to help minimize scarring, although the evidence for the effectiveness of these products is absent to minimal.
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References

SHOWING 1-10 OF 53 REFERENCES
Prevention of hypertrophic scars by long-term paper tape application.
  • R. Reiffel
  • Medicine
    Plastic and reconstructive surgery
  • 1995
TLDR
Control or elimination of such stretching forces by the long-term use of paper tape, beginning at 2 weeks, has been effective in preventing hypertrophic scarring.
Onion Extract Gel Versus Petrolatum Emollient on New Surgical Scars: a Prospective Double‐Blinded Study
TLDR
In this side-by-side, randomized, double-blinded, split-scar study, the onion extract gel did not improve scar cosmesis or symptomatology when compared with a petrolatum-based ointment.
Use of pressure to treat hypertrophic burn scars.
  • M. Staley, R. Richard
  • Medicine
    Advances in wound care : the journal for prevention and healing
  • 1997
TLDR
Pressure has been used since the early 1970s by burn care provides to help minimize the formation of hypertrophic scars and appears clinically to enhance the scar maturation process.
Adhesive contact media--an update on graft fixation and burn scar management.
Failure of topical steroids and vitamin E to reduce postoperative scar formation following reconstructive surgery.
TLDR
It is concluded that neither topical steroid nor topical vitamin E is effective in reducing scar formation after grafting procedures for reconstruction for postburn contractures.
VITAMIN E ADDED SILICONE GEL SHEETS FOR TREATMENT OF HYPERTROPHIC SCARS AND KELOIDS
TLDR
These authors demonstrated that it is not the mechanical pressure that is the mechanism of action, but a direct action on fibroblasts and a hyperhydration of subcutaneous tissue that leads to keloids.
Pilot study evaluating topical onion extract as treatment for postsurgical scars.
  • B. Jackson, A. Shelton
  • Medicine
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • 1999
BACKGROUND Post surgical scars can be erythematous, raised, pruritic and painful. Numerous modalities are available to improve the appearance and symptomatology of these scars. A topical onion gel
Cica-Care gel sheeting in the management of hypertrophic scarring.
A Randomized Controlled Trial of Hydrocolloid Dressing in the Treatment of Hypertrophic Scars and Keloids
TLDR
Evaluating a hydrocolloid dressing or moisturizer to keloids or hypertrophic scars resulted in symptomatic improvement, but no change in physical parameters.
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