Review of Dscam-mediated immunity in shrimp and other arthropods.

@article{Ng2014ReviewOD,
  title={Review of Dscam-mediated immunity in shrimp and other arthropods.},
  author={Tze Hann Ng and Yi-An Chiang and Ying-Chun Yeh and Han-Ching Wang},
  journal={Developmental and comparative immunology},
  year={2014},
  volume={46 2},
  pages={129-38}
}
Although true adaptive immunity is only found in vertebrates, there is increasing evidence that shrimp and other arthropods exhibit immune specificity and immune memory. The invertebrate immune response is now called "innate immunity with specificity" or "immune priming", and its underlying mechanisms are still unclear. However, while vertebrate antibodies have no invertebrate homolog, the Down syndrome cell adhesion molecule (Dscam), which is a hypervariable protein created by alternative… CONTINUE READING

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