Review of Astragali Radix

@article{Jing2011ReviewOA,
  title={Review of Astragali Radix},
  author={Liu Jing and Zhao Zhong-zhen and Chen Hubiao},
  journal={Chinese Herbal Medicines},
  year={2011},
  volume={3},
  pages={90}
}
Astragali Radix (AR), known as Huangqi in China, is one of the most popular herbal medicines learnt worldwide to reinforce Qi (the vital energy). AR is traditionally prepared from the dried roots of Astragalus membranaceus or A. membranaceus var. mongholicus. It has been reported to have cardiotonic, hepatoprotective, hypotensive, immunostimulant, anti-aging, anti-oxidative, antidiabetic, and anti-inflammatory activities. The bioactive compounds were found to be flavonoids, saponins… 

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References

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Comparison of the Immunoregulatory Function of Different Constituents in Radix Astragali and Radix Hedysari
TLDR
Comparison of the immunological effects of extracts of Radix Astragali and Radix Hedysari showed that flavonoids and saponins present in RA and HQ were not only structurally significantly different but also different in their immunological effect.
Inhibitory effects of Astragali Radix, a crude drug in Oriental medicines, on lipid peroxidation and protein oxidative modification by copper.
Chemical analysis of Radix Astragali (Huangqi) in China: a comparison with its adulterants and seasonal variations.
TLDR
The results showed that the amounts of main constituents such as isoflavonoids and astragalosides varied in different species, which would provide useful information for the quality control of Radix Astragali.
Quality evaluation of Radix Astragali from different sources in China = 不同来源中药黄芪的质量评价
Radix Astragali (Huangqi) is one of the most valuable traditional Chinese medicinal herbs. It is used in the traditional Chinese medicine to reinforce ‘qi’, and it has immunostimulant,
Inhibitory effects of isoflavones in roots of Astragalus membranaceus BUNGE (Astragali Radix) on lipid peroxidation by reactive oxygen species
Possible inhibitory effects were investigated of isoflavones in the roots of Astragalus membranaceus BUNGE (Astragali Radix), afrormosin, calycosin, formononetin and odoratin on lipid peroxidation by
Astragalosides isolated from the root of astragalus radix inhibit the formation of advanced glycation end products.
TLDR
Data suggest that AR and astragalosides may be a potentially useful strategy for the prevention of clinical diabetic complications by inhibiting AGEs.
Analysis of immunological enhancement of immunosuppressed chickens by Chinese herbal extracts.
Subchronic toxicity studies of Radix Astragali extract in rats and dogs.
Expression profile of a PAL gene from Astragalus membranaceus var. Mongholicus and its crucial role in flux into flavonoid biosynthesis
TLDR
Results indicate that PAL is maybe a key point for flux into flavonoid biosynthesis in the genetic control of secondary metabolism in A. membranaceus var.
Anti-hepatitis B virus activities of astragaloside IV isolated from radix Astragali.
TLDR
The results demonstrate that astragaloside IV possesses potent anti-HBV activity and is more potent than that of 3TC without significant cytotoxicity.
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