• Corpus ID: 42873222

Review article Reduced measles and varicella passive immunity and susceptible infants in the 21 ST century. Myth or reality

  title={Review article Reduced measles and varicella passive immunity and susceptible infants in the 21 ST century. Myth or reality},
  author={Machaira Maria and Critselis Elena and Papaevangelou Vassiliki},
Vaccination against measles has substantially decreased child mortality worldwide. The recent introduction of varicella immunization has significantly reduced the associated disease burden. However, there exists a period of elevated disease susceptibility among infants secondary to the diminishment of maternal passive immunity. This article reviews recent studies on transplacentally transferred antibodies against m easles and varicella. Recent Findings Both MMR and varicella vaccines are… 
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Low and Zero Prevalence Rates of Anti-measles Virus Immunoglobulin G in Mothers and Their Infants Respectively in Health Centers in Osogbo, Nigeria

The susceptibility of mother-infant pair participants to measles virus infection in two health centers in Osogbo, Osun State, Nigeria was determined to be descriptive, cross-sectional hospital-based study.

Risk factors for measles death: Kyegegwa District, western Uganda, February–September, 2015

Lack of vaccination and no treatment in a health facility increased the risk for measles deaths and the one-dose measles vaccination currently in the national vaccination schedule had a protective effect against measles death.



Early waning of maternal measles antibodies: why immunization programs should be adapted over time

An early loss of maternal antibodies in infants of vaccinated mothers but also in infant of naturally immune women should be taken into account for a timely administration of the first dose of measles vaccine, particularly in the current context of re-emerging measles in Europe.

Kinetics of Decline of Maternal Measles Virus-Neutralizing Antibodies in Sera of Infants in France in 2006

After more than 20 years of routine measles vaccination in France, maternal measles-neutralizing antibodies decrease dramatically in French infants by 6 months of age, and it is shown that 90% of infants are not protected against measles after 6 years of age.

Immune responses to measles and mumps vaccination of infants at 6, 9, and 12 months.

T cell responses can be established by immunization with these live attenuated virus vaccines during the first year, despite the presence of passive antibodies, and cellular immunity was equivalent to that of older infants.

Prevalence of Anti-Varicella-Zoster Virus Antibodies in French Infants under 15 Months of Age

Based on a large number of subjects, this study clearly demonstrated, for the first time in France, high levels of passively acquired maternal antibodies during the neonatal period, and it allowed us to estimate the duration of passive acquired maternal anti-VZV IgG in French infants.

Reduced measles immunity in infants in a well-vaccinated population.

The recommended age for measles vaccination is based in part on information gathered when most mothers had natural measles. Nowadays many mothers have received measles vaccine. To assess this change

Determining infants' age for measles vaccination based on persistence of protective level of maternal measles antibody.

The present study was conducted over a period of one year to find the right time for measles vaccination when maternal antibody titer in infants was decayed rendering them susceptible to wild virus

Increasing Coverage and Efficiency of Measles, Mumps, and Rubella Vaccine and Introducing Universal Varicella Vaccination in Europe: A Role for the Combined Vaccine

Recently registered measles-mumps-rubella-varicella (MMRV) vaccines could facilitate introduction of varicella universal mass vaccination by simplifying administration and providing the potential to achieve high coverage rates for these 4 diseases.

The clinical significance of measles: a review.

Complication rates are higher in those <5 and >20 years old, although croup and otitis media are more common in those<2 years old and encephalitis in older children and adults.