Review article: transient receptor potential channels as possible therapeutic targets in irritable bowel syndrome.

Abstract

BACKGROUND Abdominal pain in irritable bowel syndrome (IBS) remains challenging to treat effectively. Researchers have attempted to elucidate visceral nociceptive processes in order to guide treatment development. Transient receptor potential (TRP) channels have been implied in the generation (TRPV1, TRPV4, TRPA1) and inhibition (TRPM8) of visceral pain… (More)
DOI: 10.1111/apt.14294

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