Review article: the potential of interferon and nucleos(t)ide analogue combination therapy in chronic hepatitis B infection.

@article{Vigan2016ReviewAT,
  title={Review article: the potential of interferon and nucleos(t)ide analogue combination therapy in chronic hepatitis B infection.},
  author={Mauro Vigan{\'o} and Federica Invernizzi and Glenda Grossi and Pietro Lampertico},
  journal={Alimentary pharmacology & therapeutics},
  year={2016},
  volume={44 7},
  pages={
          653-61
        }
}
BACKGROUND A short-term course of pegylated-interferon (Peg-IFN), or a long-term treatment with a third generation nucleot(s)ide analogue (NUC), of chronic hepatitis B (CHB) infection achieves viral suppression and may prevent disease progression. Owing to different mechanisms of action of the two regimens, a Peg-IFN and NUC combination treatment may be an attractive approach to enhance the off-treatment rates of virological and serological response. AIM To review the literature on… CONTINUE READING
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