Review article: the nature of oesophageal injury in gastro-oesophageal reflux disease.

@article{Hertogh2006ReviewAT,
  title={Review article: the nature of oesophageal injury in gastro-oesophageal reflux disease.},
  author={Gert de Hertogh and Nadine L Ectors and Peter Van Eyken and Karel Geboes},
  journal={Alimentary pharmacology & therapeutics},
  year={2006},
  volume={24 Suppl 2},
  pages={
          17-26
        }
}
The purpose of this review was to explore issues relating to the nature of oesophageal injury in gastro-oesophageal reflux disease. Several structural and functional elements of the oesophageal epithelium provide for an inherent resistance against refluxed material. It is only when this defence is overcome that reflux-induced damage ensues. The light microscopic changes in reflux oesophagitis are manifold. Early changes are confined to the epithelium and consist of reactive changes and… CONTINUE READING
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