Review article: the extra‐skeletal effects of vitamin D in chronic hepatitis C infection

@article{Cholongitas2012ReviewAT,
  title={Review article: the extra‐skeletal effects of vitamin D in chronic hepatitis C infection},
  author={Evangelos Cholongitas and Eleni Theocharidou and John Goulis and Emmanuel A. Tsochatzis and Evangelos A. Akriviadis and A. K. Burroughs},
  journal={Alimentary Pharmacology \& Therapeutics},
  year={2012},
  volume={35}
}
Recent interest has focused on the extra‐skeletal effects of vitamin D, in particular, in patients with chronic hepatitis C. 
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The association between serological and dietary vitamin D levels and hepatitis C‐related liver disease risk differs in African American and white males
TLDR
Vitamin D may affect the severity of HCV‐related liver disease and the need for vitamin D supplementation in patients with liver disease.
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Recent updates on vitamin D and pediatric gastrointestinal diseases
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This article reviews recent publications, regarding vitamin D deficiency and childhood gastrointestinal diseases, and introduces new treatment and prevention guidelines foritamin D deficiency.
Vitamin D in chronic liver disease
Chronic liver disease (CLD) and several related extrahepatic manifestations such as hepatic osteodystrophy are associated with deficiency of vitamin D, which has therefore been suggested as…
Is there an association between vitamin D and liver fibrosis in patients with chronic hepatitis C?
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In this study, no association was observed between vitamin D and inflammatory activity, as well as the degree of liver fibrosis, in patients with chronic hepatitis C.
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Theoretically, an optimal Vitamin D supplementation might favor operational tolerance and protect transplant recipients from the triad cardiovascular disease-cancer-infection, but more solid data are needed to confirm this and to set the optimal level of serum Vitamin D supplements in order to attain the best clinical outcome.
Detrimental Impact of Interferon-Based Regimens for Chronic Hepatitis C on Vitamin D/Parathyroid Hormone Homeostasis
TLDR
An increase in plasma PTH occurs systematically during IFN treatment of HCV patients and cannot be prevented by vitamin D supplementation, and there is no statistical correlation between vitamin D and PTH blood levels.
Will vitamin d supplementation have a role in the treatment of patients with chronic hepatitis C?
  • P. Puri
  • Medicine, Biology
    Journal of clinical and experimental hepatology
  • 2012
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