Review article: the chemoprevention of colorectal carcinoma.

  title={Review article: the chemoprevention of colorectal carcinoma.},
  author={Christoph Gasch{\'e}},
  journal={Alimentary pharmacology & therapeutics},
  volume={20 Suppl 4},
This review aims to provide an insight into some of the common pathways involved in the development of colorectal cancer--so-called chromosomal instability and microsatellite instability. There is both clinical and molecular evidence to show that colorectal cancer development occurs over an extended period of time. Together with a knowledge of the molecular pathogenesis of colorectal cancer, this time window allows physicians to counteract cancer development, a strategy known as chemoprevention… CONTINUE READING