Review article: short chain fatty acids in health and disease.

@article{Cook1998ReviewAS,
  title={Review article: short chain fatty acids in health and disease.},
  author={Susan Lynn Cook and Joseph H. Sellin},
  journal={Alimentary pharmacology & therapeutics},
  year={1998},
  volume={12 6},
  pages={
          499-507
        }
}
Short chain fatty acids (SCFAs) have been the subject of much research over the past few decades. They play a vital role in maintenance of colonic integrity and metabolism. They are produced when dietary fibre is fermented by colonic bacteria. SCFAs are avidly absorbed in the colon, at the same time as sodium and water absorption and bicarbonate secretion. Once absorbed, SCFAs are used preferentially as fuel for colonic epithelial cells and have trophic effects on the epithelium. Clinically… CONTINUE READING
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