Review article: role of pepsin and bile in gastro-oesophageal reflux disease.

  • Jan Tack
  • Published 2005 in Alimentary pharmacology & therapeutics


Gastro-oesophageal reflux disease is defined as the presence of symptoms or lesions that can be attributed to the reflux of gastric contents into the oesophagus. Aspiration and prolonged monitoring studies in humans have shown that reflux of gastric contents is comprised of both acid and non-acid components, in healthy as well as diseased people. Methods to… (More)