Review article: new developments in the use of 5-aminosalicylic acid in patients with inflammatory bowel disease.

Abstract

Sulphasalazine is composed of sulphapyridine and mesalazine (5-aminosalicylic acid, 5-ASA or mesalazine) joined by an azo bond. Sulphasalazine has been used clinically for 40 years but less than 10 years ago it was recognized that the active moiety is 5-ASA. Sulphapyridine appears to act only as a carrier molecule to deliver mesalazine to the bowel, yet it… (More)

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Cite this paper

@article{Thomson1991ReviewAN, title={Review article: new developments in the use of 5-aminosalicylic acid in patients with inflammatory bowel disease.}, author={Alan B. R. Thomson}, journal={Alimentary pharmacology & therapeutics}, year={1991}, volume={5 5}, pages={449-70} }