Review article: immunopathogenetic and therapeutic aspects of autoimmune hepatitis.

@article{Medina2003ReviewAI,
  title={Review article: immunopathogenetic and therapeutic aspects of autoimmune hepatitis.},
  author={Jes{\'u}s Medina and Luisa C Garc{\'i}a-Buey and Ricardo Moreno-Otero},
  journal={Alimentary pharmacology & therapeutics},
  year={2003},
  volume={17 1},
  pages={1-16}
}
Autoimmune hepatitis is a chronic, progressive liver disease that responds well to immunosuppressive therapy, but has a poor prognosis if untreated. Possible triggering factors include viruses, other autoimmune disorders and drugs. The molecular mechanisms contributing to the pathogenesis include: reactions of autoantibodies against their corresponding autoantigens; aberrant expression of histocompatibility antigen class I and II molecules, cell adhesion molecules and cytokines; increased… CONTINUE READING

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