Review article: genetic factors that modify the outcome of viral hepatitis.

  title={Review article: genetic factors that modify the outcome of viral hepatitis.},
  author={Albert Friedrich Staettermayer and T Scherzer and Sandra Beinhardt and Karoline Rutter and Harald Hofer and P Ferenci},
  journal={Alimentary pharmacology & therapeutics},
  volume={39 10},
BACKGROUND Genetic factors can play an important role for treatment response and disease progression in chronic viral hepatitis. AIM To review the influence of host genetic factors on the clinical course as well as on treatment response in patients with viral hepatitis. METHODS Review of the literature. RESULTS A landmark genome-wide association study (GWAS) identified polymorphisms in the IL28B gene on chromosome 19 (19q13.13) associated with response to therapy with pegylated interferon… CONTINUE READING
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