Review article: exploring the link between Helicobacter pylori and gastric cancer

  title={Review article: exploring the link between Helicobacter pylori and gastric cancer},
  author={E. Kuipers},
  journal={Alimentary Pharmacology & Therapeutics},
  • E. Kuipers
  • Published 1999
  • Medicine
  • Alimentary Pharmacology & Therapeutics
  • Cancer of the distal stomach, both of the intestinal and diffuse type, is strongly associated with Helicobacter pylori colonization. This bacterium causes chronic active inflammation of the gastric mucosa in the majority of colonized subjects. In a considerable number of them, this will eventually lead to a loss of gastric glands, and thus the establishment of atrophic gastritis, which is associated with the development of intestinal metaplasia and dysplasia. Development of atrophy and… CONTINUE READING
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