Review article: aspirin and gastrointestinal bleeding.


Many animal and human studies have shown aspirin to cause gastric mucosal erosions and enhanced spontaneous microbleeding. Chronic use is associated with uncomplicated gastric ulcer (but not clearly with uncomplicated duodenal ulcer) and with presentation with haematemesis and melaena. Sub-group analysis suggests that the risks of bleeding duodenal ulcer as… (More)


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