Review article: acid-related disease--what are the unmet clinical needs?

@article{Katz2006ReviewAA,
  title={Review article: acid-related disease--what are the unmet clinical needs?},
  author={Philip O. Katz and James M. Scheiman and Alan N Barkun},
  journal={Alimentary pharmacology & therapeutics},
  year={2006},
  volume={23 Suppl 2},
  pages={9-22}
}
Proton pump inhibitors have dramatically improved the management options available for patients with acid-related disorders. In patients with gastro-oesophageal reflux disease, currently available proton pump inhibitors provide an excellent outcome for the majority; however, they do not provide optimal pH control in many. Proton pump inhibitors co-therapy reduces, but does not eliminate, the risk of gastrointestinal ulcers and complications in patients taking non-steroidal anti-inflammatory… CONTINUE READING