Review article: Efficacy and safety of methoxyflurane analgesia in the emergency department and prehospital setting

@article{Grindlay2009ReviewAE,
  title={Review article: Efficacy and safety of methoxyflurane analgesia in the emergency department and prehospital setting},
  author={Joanne Grindlay and Franz E. Babl},
  journal={Emergency Medicine Australasia},
  year={2009},
  volume={21}
}
This article reviews the evidence for the analgesic efficacy of methoxyflurane in both prehospital and ED settings, as well as the adverse event profile associated with methoxyflurane use. Although there are no published controlled trials of methoxyflurane in sub‐anaesthetic doses, available data indicate that it is an efficacious analgesic. There is inadequate evidence regarding its use as an agent for procedural pain. Despite the potential for renal impairment evident when it was used in… 
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References

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Objective:  For many years, ambulance services throughout Australia have been administering methoxyflurane as a first‐line analgesic agent. However, there is a paucity of literature regarding its
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TLDR
A pilot study to explore Methoxyflurane's use as a patient controlled analgesic for painful procedures in children in the emergency department (ED) of a hospital in Australia.
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TLDR
This paper is a preliminary communication on the use of subnarcotic concentrations of methoxflurane as a pain relieving drug in labour and to determine what place, if any, it may have among inhalation agents already used for this purpose.
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TLDR
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TLDR
A field trial of 1,257 patients receiving methoxyflurane, trichloroethylene, and nitrous-oxide/oxygen for the relief of pain in labour confirmed the objective method for screening an inhalational agent as an obstetric analgesic.
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TLDR
Since definite alterations in the indices of both hepatic and renal functions were recognized in obstetrical personnel following exposure, a re-evaluation of the use of methoxyflurane for obstetrical analgesia is suggested.
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TLDR
Since definite alterations in the indices of both hepatic and renal functions were recognized in obstetrical personnel following exposure, a re-evaluation of the use of methoxyflurane for obstetrical analgesia is suggested.
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TLDR
Methoxyflurane has been used to provide analgesia for burns dressings on sixty occasions in eleven patients by way of a new, disposable vaporizer, the Analgizer, which is described.
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